In combination with the progress of age, wrinkles and sarcomas occur. The fillers applied to the face, also called Dermal fillers and injections, are applied in different density and type to different parts of the face.

Fillers applied to the face can be applied to different depths, ranging from deep to subdermal area to dermal area. The application depth varies according to the type of filler and the depth of skin defect or wrinkle. These fillers fill the folds and wrinkles around the mouth and eyes with success and continue their persistentness to 1-1.5 years.